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One previous study has reported that the suppression of ABHD6 can prevent diet-induced obesity and increase 1-MAG levels, enhancing adipose browning and brown adipose function through PPARa/ activation

Data availability All relevant data are within the paper and its Supplementary Information files

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However, further experimental studies are required to substantiate the mechanism by which topiramate modulates these pathways and to confirm its efficacy in treating migraines

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