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Zheng, Y., Ley, S

The alkyl groups are removed from the amino group by the process of oxidation

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Such a non-protein cofactor is known as a "prosthetic group." R -lipoic acid functions as a prosthetic group for the biological activity of the following multienzyme complexes: The glycine cleavage system that catalyzes the decarboxylation of glycine coupled with the addition of a methylene group (-CH 2 ) to tetrahydrofolate to form 5,10-methylene tetrahydrofolate, an important cofactor in the synthesis of nucleic acids ( Figure 3 )

These ROS molecules, which include superoxide and hydrogen peroxide, cause oxidative damage to cells by destroying lipids, proteins, and DNA (51)