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The mice were housed and bred under specific pathogen-free conditions at the Luxembourg Institute of Health (LIH) and the BTA facility of the University of Luxembourg

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4.5 Septicemia Bacterial inflammation triggers significant oxidative stress, during which the metabolism of oxidized phospholipids is regulated, at least in part, by mitochondrial -oxidation pathways (61)

Nrf2 silencing abrogated Met- and L-car-induced upregulation of BAT-related genes in mouse adipocytes To decipher the role of Nrf2/HO-1 signaling in Met and L-car-induced browning of adipocytes, 3T3-L1 cells were induced to differentiate into mature adipocytes following Nrf2 silencing