All analyses were performed with the use of SAS software, v.9.4 (SAS Institute) and GraphPad Prism v.8.4.3
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An efficient baseline enzymatic transformation of these molecules may yield a distinct ligand profile capable of co-activating host farnesoid X receptor (FXR) and G protein-coupled bile acid receptor TGR5 pathways, thereby synergizing with the exogenous drug to improve metabolic flexibility (80)
Thats so the lab doesnt know where its coming from, he said