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Joint and muscle discomfort are occasionally reported with GLP-1 medications, but they are not among the most common side effects

So it will not cause any side effects in the stomach, intestines or thyroid

Every plan also includes our GLP-1 Nutrition Protocol, designed specifically around how this medication changes your appetite and metabolism

TRIUMPH-1 results indicate more substantial weight reduction with Retatrutide, but lack of head-to-head trials means we must treat these findings cautiously

As NPR reported in early 2026, no national guidelines currently require eating disorder screening prior to GLP-1 prescribing

Gastrointestinal side effects including nausea, vomiting, diarrhea, and constipation remain the most common adverse effects and occur more frequently at the 7.2 mg dose (approximately 71%) than at 2.4 mg (approximately 61%)