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Acetyl tributyl citrate, the most widely used phthalate substitute plasticizer, induces cytochrome p450 3a through steroid and xenobiotic receptor

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This reduction was prevented by MG132 (proteasome inhibitor) but not Lys05 (lysosome inhibitor), indicating that SLC7A11 protein is degraded via the ubiquitin-proteasome pathway rather than the lysosomal pathway [47]

doi: 10.1029/2005GL022375 66 MaceyM

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