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1:1 ratio

and thats why we sometimes need to supplement

Lowering inflammatory cytokines Studies in Nature and Diabetes show that GLP-1 reduces cytokines such as TNF-alpha, IL-6, and IL-1, which are major players in autoimmune diseases and arthritis

In PIONEER 8, compared with patients receiving basal or premixed insulin, patients receiving basal-bolus insulin appeared to have a greater duration of diabetes (13 and 14 years vs 16 years, respectively), greater body weight (85 and 78 kg vs 89 kg) and a higher total daily insulin dose (35 and 48 U vs 79 U) (Table 2(ii))

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