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If you take a standard capsule or tablet, the enzymes in your stomach often break the peptide bonds before the glutathione ever reaches your small intestine

However, the metabolic activation and protein adduct formation, also in mitochondria, are only marginally lower in rats compared to mice but there was no relevant mitochondrial dysfunction and oxidant stress in rats [124]

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doi:10.1016/j.hrthm.2024.11.047