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From each subject, a detailed brain image was first acquired, using a magnetization-prepared rapid gradient echo 47 high-resolution T1-weighted sequence (repetition time=6.6 ms, echo time=3.0 ms, flip angle=8, matrix=256240, slices =170, and slice thickness=1 mm)

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However, mutations in the MTHFR gene typically result in a lack of folate required for methylation reactions

doi: 10.1146/annurev.genom.6.080604.162324 41 Genetic Analysis of Psoriasis Consortium & the Wellcome Trust Case Control Consortium

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