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Moreover, semaglutide was associated with a 17% reduction in loop diuretic dosage compared to a slight increase in the placebo group over the study period

However, this isn't set in stone

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The FDA characterized Novos violations and subsequent responses as suggest[ing] systemic failures with your surveillance, receipt, evaluation, and reporting of ADEs to FDA, and noted that their failure to determine the root causes of the violations raises concerns about your firms ability to monitor the safety of your products. I wrote about this here