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Immunity, inflammation, and cancer

Immunol 162 (2), 160178

In addition, BSO decreased the intensity of Ki67 staining and increased that of 4-HNE staining in tumors with high ACTL6A expression, but this trend was not observed in PDX tumors with low ACTL6A expression (Supplementary Fig 8b)

It was identified relatively recently as a mitochondria-derived signalling molecule with systemic metabolic and anti-inflammatory effects

Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria