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For this reason, and similar to a previous study (13), we used GLP-1R expression in these islets as an internal positive control for the immunohistochemical analysis

Given the limitations of the in vitro model using one human adipocyte cell line, further studies are necessary to confirm the hypothesis that nutrients, by stimulating the secretion of GLP-1, may influence the expression of irisin and thus modulate the mitochondrial metabolism of adipocytes.

Mechanism, structure-activity studies, and potential applications of glutathione S -transferase-catalyzed cleavage of sulfonamides