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Together, these findings suggest a broad anti-craving or anti-reward effect rather than substance-specific action

GLP-1 (glucagon-like peptide-1) agonists have emerged as promising agents for cardiovascular therapeutics, owing to their profound metabolic and cardioprotective effects [4]

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These FDA-approved treatments work by mimicking the natural hormones your body releases during digestion, helping regulate appetite, slow stomach emptying, and improve blood sugar control

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With respect to non-glycaemic outcomes, GLP1-RAs promote weight loss and have been investigated in randomised placebo-controlled trials focusing on cardiovascular outcomes in adults with type 2 diabetes and high cardiovascular risk