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Immunoreactivity studies localize PKCs widely in the CNS, including in olfactory bulb, cerebral cortex (I, IV), pyriform cortex, hippocampus (CA1 stratum radiatum and oriens), amygdala (central and basolateral nuclei), and cerebellum (molecular cortex) (Saito et al., 1988)

Superoxide anions are one of the strongest reactive oxygen species (ROS) and contribute to many health challenges

Exp Ther Med 25:145

Methionine adenosyltransferase 1 is targeted to the mitochondrial matrix and interacts with cytochrome P450 2E1 to lower its expression

Expression of TNF-, a target for NF-B and a cytokine strongly implicated in estrogen-deficiency bone loss, was suppressed in osteoclasts by 17- estradiol and NAC