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It doesn't bind to GLP-1 receptors, insulin receptors, or glucagon receptors

Evaluation of novel TGR5 agonist in combination with Sitagliptin for possible treatment of type 2 diabetes

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Ethical approval for this study was obtained We have complied with all relevant ethical regulations for animal use

5.3.6 Dopamine Recent studies have demonstrated that certain gut microbes can synthesize dopamine or its precursors through specific metabolic pathways, thereby indirectly regulating host physiological functions, and dopamine can stabilize GPX4 and mitigate ferroptosis-related oxidative stress (171)

Br J Dermatol (2012) 166(6):118497