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McGraw-Hill (Lange)

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Historical cosmetic and preclinical data suggest that topical copper peptides may improve hair shaft diameter and reduce shedding, yet controlled, large-scale clinical trials are sparse

Biochem Pharmacol 39:5965 Schnleben-Janas A, Kirsch P, Mittl PR, Schirmer RH, Krauth-Siegel RL (1996) Inhibition of human glutathione reductase by 10-arylisoalloxazines: crystalline, kinetic, and electrochemical studies

Both sit at the preclinical tier mechanistically plausible, supported by cell-culture and animal studies, but not confirmed by controlled human trials

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