Whilst Wegovy improves glycaemic control in patients with diabetes, patients may still experience fluctuating glucose levels during the initial treatment period
The concept of escalation and maintenance therapy represents a strategy that gives precedence to safety over efficacy and, if necessary, to sequentially advance in the treatment pyramid.Reference Fenu, Lorefice, Frau, Coghe, Marrosu and Cocco 67 - Reference Du Pasquier, Pinschewer and Merkler 69 In this approach, individuals start with first-line agents and are switched to second- or even third-line agents if they exhibit breakthrough disease that pushes them from low to high in terms of the risk for imminent disease progression
Persistent hyperglycaemia induces deleterious changes in kidney cellular metabolism and function through a variety of mechanisms
The cycle would continue week after week
We've known that for several years now
Maintenance dose pricing varies based on manufacturer and platform structures