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For testing the difference in mean and median lifespan between groups, we used linear mixed model with linear quantile mixed-effects model, which included cage assignment as a random effect and batch as a covariate, respectively, using package nlme and lgmm in statistical software R

Finally, it is important to highlight the immunomodulatory effects of tirzepatide

NAD+ helps reduce oxidative stress, supporting long-term health as you lose weight

Mucociliary clearance enhancement Dysfunctions of the airway mucus barrier can arise owing to infectious diseases, chronic respiratory conditions and physical injuries such as respiratory tract burns

IGF-1-LR3 is a modified, longer-acting version of insulin-like growth factor 1 (IGF-1), a peptide associated with the body's natural growth, recovery, and tissue-repair signaling pathways

It consists of three stages: stage 1 planning, stage 2 risk-of-bias assessment for specific results, and stage 3 overall risk-of-bias assessment