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1 The different GLP-1 RAs vary in the number of antibodies seen in clinical trials, with exenatide (once weekly) having the greatest and dulaglutide and albiglutide having the least

D.KeY.et al

Tirzepatide, a dual glucagon-like peptide-1 (GIP) and GLP-1RAs, administered once weekly at a 15 mg dose, resulted in an average weight loss of 20.9% over 72 weeks (Jastreboff et al., 2022), driven by its synergistic effects on appetite regulation, energy intake reduction, and fat mass decrease (Heise et al., 2023)

This study aims to promote the understanding of the disease mechanism by summarizing the regulatory role of Th17/Treg in AR, and provide valuable insights for the development of innovative treatment models

Nishtar Medical University and Hospital, Multan, Pakistan (Shah)

doi: 10.1038/ijo.2011.158 89 AstrupARssnerSVan GaalLRissanenANiskanenLAl HakimMet al