For patients with type 2 diabetes, alternative glucose-lowering medications may need to be initiated or adjusted before stopping semaglutide, along with a plan for blood glucose monitoring
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So by far, these injectables are the most appropriate for people who have heart disease or polypharmacy, meaning they take a long list of medications
Using both together increases the risk of significant constipation
They slip past the drugs appetite brakes
Patients should never stop GLP-1 treatment for type 2 diabetes without consulting their healthcare provider, as this may cause deteriorating blood glucose control