Iron overload (a hallmark of asthma) enhances ROS production via Fenton reactions (102)
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In recent years, it has been proposed that UC can be treated by inhibiting ferroptosis to reduce intestinal epithelial cell damage and protect the structure and function of the intestinal barrier
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Selenium and Glutathione Production Selenium does not create glutathione
Specifically, significant enrichment observed in pathways associated with energy metabolism, including tricarboxylic acid (TCA) cycle intermediates and fatty acid -oxidation and alterations in amino acid metabolism pathways, particularly those involving glutathione metabolism, emphasized the role of NAC in maintaining cellular redox homeostasis