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doi: 10.1038/s41598-018-23623-9 50 HondaTKabashimaK

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Acetaminophen affects the survivor, pigmentation and development of craniofacial structures in zebrafish (Danio rerio) embryos

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R471C has been shown to localise to the membrane and has ~15% activity of wildtype OCTN2 in CHO cells, which is consistent with the observed reduction in currents for R471A, meanwhile Y358N in CHO cells has ~8% activity, though localisation data for Y358N is unavailable 11,50