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Despite a lack of data on GSH concentrations in tissues, these authors proposed that the benefits of dietary glycine supplementation might be mediated by GSH synthesis and antioxidant capacity [36]

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( f-g ) H4K12ac or H3K23ac chromatin immunoprecipitation in U2OS-mCherry-LacI-Fok1 cells treated with the IDH1 inhibitor ( f ) or transduced with shRNA targeting TMLHE (shTMLHE) ( g ) alone or supplemented with KG or l-carnitine (l-carn) supplementation (n = 3 technical replicates representative from 2 independent experiments)

Again, this is likely due to an improved blood flow due to a higher nitrate concentration