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Potential Side Effects Nausea (most common, reported in ~40% of users, usually mild and transient) Flushing or warmth sensation Increased blood pressure (short-term effect) Fatigue or dizziness Spontaneous erections (in men) While generally well-tolerated, PT-141 should be used cautiously in individuals with cardiovascular issues, hypertension, or a history of stroke, as it can cause mild increases in blood pressure

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Immune checkpoint inhibitors cause immune dysregulation by blocking inhibitory signals that normally regulate T-cell activation, leading to an unchecked immune response

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