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Autophagy Activation: Fasting is well known to accelerate autophagy, a normal process wherein damaged cells are eliminated and replaced with fresh, healthy ones

Regardless of the initial insult, oxidative bursts through NOX and increased oxidative phosphorylation in the mitochondria induce metabolic alterations responsible for observed interictal glucose hypometabolism

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If the sulfation pathway is defective, as has been shown in autism, and/or there is impaired glucuronidation, acetaminophen will be increasingly converted to the alternative metabolic routes, increasing production of its more toxic compounds NAPQI and AM404

Thus, providing the suitability of the both models, and damaging regimens used, these arguments ( i.e