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In fact the ELF concentration of GSH is 140 times that of blood serum concentrations

GCLC knockout mice die within a month of birth due to the absence of hepatic GSH synthesis

Smith, J.A., et al

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The umbrella term NAFLD includes the pure liver fat accumulation, the so-called hepatic steatosis or non-alcoholic fatty liver, and the progressive form with inflammation, also known as non-alcoholic steatohepatitis, which is related to the increase in oxidative stress and reactive oxygen species, eventually leading to liver fibrosis