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The medication is suitable for patients who are not currently treated with metformin as well as those who are already taking metformin

But its made by a licensed compounding pharmacy

300 min per week may increase HDL-C concentration by 0.15 mmol/l (6 mg/dl) [128]

In my practice, we approach discontinuation carefully: Gradual taper when appropriate Maintenance nutrition plan Structured exercise Continued metabolic monitoring Some patients benefit from extended maintenance therapy

This is consistent with previous studies (Sun et al., 2012

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