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Cancer cells produce significantly higher amounts of ROS than normal cells and therefore administration of prooxidant agents capable of further increase of ROS may represent a potential anticancer approach
Wu J, et al
Key monitoring recommendations: Get your IGF-1 levels checked before starting, and check them every 12 weeks during use
Effect of bee venom on sexual efficiency in normal and hydrogen peroxide treated adult male rats
More recently, the use of IPI504 (Retaspimycin, a synthetic derivative of Geldanamycin), in an in vitro model of age-related macular degeneration (AMD) on senescent ARPE-19 (human arising retinal pigment epithelial cells), leads to a decrease of SA--Galactosidase positive cells, associated with a downregulation of senescence-associated gene expression as well as SASPs secretion, suggesting that in some cases HSP90 inhibitors could also be used as senomorphics 27
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