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Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

Glutathione is a tripeptide, which is a small protein-like molecule made of three specific amino acids: glutamic acid , cysteine , and glycine

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We used mouse tumor xenograft model by orthotopically injecting luciferase-labelled Hepa1-6, a mouse hepatoma cell line, into immunocompetent C57BL/6 mice (Fig

In line with this possibility, conditions that result in increased cholesterol accumulation in lysosomes such as the use of tricyclic antidepressants can potentiate APAP hepatotoxicity