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Brains were later sectioned on Leica CM3000 cryostat, and 1 mm punches (Integra Miltex Biopsy Punch) of the hypothalamus, hippocampus and hindbrain were collected

Strictly for in-vitro research use only

Participants received either semaglutide 2.4 mg weekly or placebo, combined with lifestyle intervention, for 68 weeks

It had earlier updated the product information to include the small risk of severe acute pancreatitis in patients taking GLP-1s

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