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The American Diabetes Association Standards of Care recommends dose reductions of insulin (by 10-20%) and sulfonylureas when initiating GLP-1 receptor agonists to minimize hypoglycemia risk

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Hold the syringe at a 90-degree angle for most areas of the body, or at a 45-degree angle if injecting into a thinner area of skin

The combined use of these medications was first reported in 2014 [61], and the number of studies has grown exponentially since then