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The B12-IF complex is absorbed by cells in the final section of the small intestine (the ileum), where IF is cleaved from B12 and subsequently, B12 passes into the blood where transport proteins bind to it and is distributed to cells all around the body (Obeid et al., 2015

BMC Genomics 26:218

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A 2008 study demonstrated a significant decrease in Th17 cells in the GI tract of patients with HIV compared with people without HIV [58]

Insights from our findings suggest a potential metabolic therapeutic strategy to enhance the anti-tumor activity of CAR T cells in patients