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More serious but less common risks include pancreatitis (characterized by severe abdominal pain that may radiate to the back), gallbladder disease, and acute kidney injury from volume depletion

Mistake 2: Shaking the vial to dissolve Vigorous shaking creates shearing forces between liquid layers that can damage peptide bonds

Inject at a 90-Degree Angle Hold the syringe or pen like a pencil and insert the needle straight into the skin at a 90-degree angle

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About 25% experienced vomiting

Over time, this can lead to irregular periods, missed ovulation, or your period stopping altogether (called weight loss-related amenorrhea)