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GHK-Cu is predominantly found in saliva, blood, and urine, and has multiple biological actions when administered to test subjects, including [1]: Antioxidant gene activity [2] Suppression of inflammatory cytokine interleukin-6 [2] Increased protein accumulation [3] Increased collagen synthesis [3] In animal models, GHK-Cu has been shown to increase an anti-inflammatory proteogly called decorin that can protect diabetic rats from kidney-damaging fibrosis [2, 4]
Immunology 85:5449
Whillier et al., 2009
In fact, the addition of NBDHEX, a strong and specific inhibitor of e-GST and other GST isoenzymes belonging to the alpha, pi and mu classes, 13 did not suppress this additional GST activity (Figure 2b), and curiously the activity was also found in the absence of GSH (Figure 2a)
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