Interestingly, GSAAT(WT), GSAAT(C138S) and GSAAT(C396S) lines were still markedly redox responsive, and exhibited up to 20% higher enzyme activity when supplied with DTT relative to the UT control conditions, while the two gsa2 lines expressing GSAAT(C168S) and GSAAT(C190S) resulted only in 9% and 2% increased GSAAT activity upon addition of DTT to the extracts ( Supplementary Figure 3E )
The study was published in the New England Journal of Medicine
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matrix metalloproteinase-9 (MMP-9), S100 calcium-binding protein A8 (S100A8), S100 calcium-binding protein A9 (S100A9), Bv8, and high mobility group box 1 (HMGB1) (169, 170)
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Longitudinal changes in fasting and glucose-stimulated GLP-1 and GIP in healthy older subjects