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Vitamin B12 is completely water-soluble, meaning your body safely flushes out any excess, making toxicity non-existent

Using bacteriostatic water is the professional standard to prevent bacterial growth for multi-use vials

The standard and accepted guideline is that an opened vial of bacteriostatic water should be discarded 28 days later, regardless of how much solution is left

The dose of vitamin B12 shots depends on how bad the deficiency is and the type of B12 used

Nat Rev Dis Primers 6

However, if youre experiencing cramps without strenuous exercise, other factors could be at play, such as: Insufficient blood flow: Reduced blood circulation to the muscles can deprive them of essential nutrients and oxygen, increasing the likelihood of cramps