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Verma S, Poulter NR, Bhatt DL, Bain SC, Buse JB, Leiter LA, et al

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Several independent studies have also shown that treatment with arimoclomol, a co-inducer of heat shock proteins, is protective against toxic mutant SOD1 aggregates, delays disease progression and improves motor function in SOD1 G93A mice (Kieran et al., 2004

GSH also acts as an intracellular sulfhydryl buffer, maintaining exposed SH groups on proteins and enzymes in the reduced state