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While it is important to note that most evidence remains preclinical, the breadth and consistency of findings across different research models provides a strong foundation for understanding the compound therapeutic potential

JAMA psychiatry 76 , 426434 (2019)

Food and Drug Administration (FDA) or any other global regulatory authority for prescription or human use

During injury states, the peptide helps regulate the inflammatory response, reducing the overproduction of pro-inflammatory cytokines that can perpetuate pain and tissue damage

Reduced Pro-Inflammatory Cytokine Activity: TNF-alpha and IL-6 expression decreases in BPC-157-treated injury sites, shortening the acute inflammatory phase that precedes productive tissue remodeling

This suggests that proinflammatory cytokines may contribute not only to neuroinflammation but also to altered neurotransmitter metabolism, further linking inflammation to depression [114]