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The endothelial damage, release of TF and intravascular TF, and elevated proinflammatory cytokines trigger immunothrombosis in the pulmonary microvasculature, yielding microclots [15]

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The improvement in serum IGF-1 with resistance exercise (two sets of 10 repetitions at 75% 1RM) is also present in older adults with MCI, though these changes in IGF-1 were not associated with improvements in cognition (Tsai et al., 2018)