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The resin consists of cross-linked agarose beads functionalized with iodoacetyl groups, typically at the end of a spacer arm

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The BBB is now known to be composed of a mixture of endothelial cells, astrocytes, and pericytes that together form the neurovascular unit (NVU) which forms a dynamic barrier and regulates the transit of molecules through this firewall of the bodys central processing unit (Fig