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Apr 10 2000;160(7):931-936

I have had to give up so much - gluten, dairy and sugar - life wouldn't be worth living if I couldn't have wine as well

The development of SKF 38393, the first D 1 -like receptor agonist, held significance for the differentiation between activation of D 1 -like and D 2 -like receptors, although it was later understood that the partial agonist nature of SKF 38393 produced an under-appreciation of the contribution of D 1 -like receptors to behavior

This off-target binding is the likely contributor to its cortisol and ACTH co-secretion, as it stimulates the hypothalamic-pituitary-adrenal axis in addition to the GH axis