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Vitamin D deserves separate mention because fat loss releases stored vitamin D from adipose tissue, temporarily increasing blood levels, but long-term reduced fat intake can lead to deficiency

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Accessible surface area (ASA) calculations In order to predict potential epitope exposed to the immune system unshielded by glycosylation, the ASA was computed for each model as well as de-glycosylated model using FreeSASA according to the Lee & Richards algorithm 17

K.CampbellS.ShuX.SawyerL.RichardsonW.et al (2010)

In preclinical models of glaucoma and DR, GLP-1RAs have demonstrated robust neuroprotective effects in ocular tissues, primarily by modulating oxidative stress, inflammation, mitochondrial function, and synaptic plasticity [42, 43]

doi: 10.1677/joe.1.06887 85 BorstSEQuindryJCYarrowJFConoverCFPowersSK