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Together, these findings identify MC4R as a major regulator of systemic energy balance

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Hanatani, K

This led researchers to conclude that epithalon may prolong the lifespan of cells and organisms [4]

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However, despite these advancements, a significant challenge that persists is the subset of patients who are resistant to or have limited response to immunotherapy (170), particularly in patients with low tumor mutational burden and immunogenic neoantigens (171, 172)