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These region-specific KP responses likely contribute to distinct depressive symptoms: altered amygdala activity may underlie increased fear and anxiety, while changes in the hippocampus and prefrontal cortex may disrupt cognition and emotional regulation

An analysis of N-acetylcysteine treatment for acetaminophen overdose using a systems model of drug-induced liver injury

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MPO converts hydrogen peroxide and chloride anions to hypochlorous acid and protects the organism against toxins and pathogens

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Cell 187 , 23752392.e33 (2024)