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Patients were followed up 085 months, with a mean of 30.4 months

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In addition to contributing to the relatively small sample size, we hypothesize that GlyNAC has an effect on PGC-1 levels mainly in the early stage of injury to promote functional recovery, but PGC-1 levels in skeletal muscle remain relatively stable in the chronic phase

Any unexpected symptom that develops after initiating the combined protocol should be evaluated in the context of potential compound interactions

The most commonly reported adverse effects are gastrointestinal , including: Nausea Bloating and flatulence Diarrhoea (particularly at higher doses above 12 g daily) Abdominal discomfort These effects are typically mild and often resolve with continued use or dose reduction