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Semaglutide activates only the GLP-1 receptor, while tirzepatide activates both GLP-1 and GIP receptors, creating dual-pathway hunger suppression

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Mol Psychiatry 2022:1 Tsai SY, Chen HJ, Chen C, Lio CF, Kuo CF, Leong KH, Wang YT, Yang TY, You CH, Wang WS (2019) Increased risk of chronic fatigue syndrome following psoriasis: a nationwide population-based cohort study