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The safety and efficacy of once-weekly glucagon-like peptide-1 receptor agonist semaglutide in patients with type 2 diabetes mellitus: a systemic review and meta-analysis

04Microdosing & Split Dosing Some researchers split their weekly GLP-1 dose across 23 injections to reduce peak-trough swings

Rybelsus is the brand name for oral semaglutide, a pioneering medication designed for the management of type 2 diabetes

It is also approved to treat moderate-to-severe obstructive sleep apnea in overweight adults

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Preclinical studies in rodent and non-human primate models have examined its effects on glucose regulation, insulin secretion, body weight, and metabolic markers