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TDP-43 is elevated in plasma neuronal-derived exosomes of patients with Alzheimers disease

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Materials and methods Ethic statements The animal studies were carried out in strict accordance with the Detailed Rules for the Administration of Animal Experiments for Medical Research Purposes issued by the Ministry of Health of the Peoples Republic of China and were approved by the Animal Experiment Administration Committee of The Fourth Military Medical University

In breast cancer, RNF5 loss is associated with increased ASCT2 expression, finally leading to poor patient outcomes, and poor response to paclitaxel (Jeon et al., 2015)

This allows the peptide to act on the central nervous system (CNS) when applied via injection or intranasally [3]