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All experimental procedures adhered to the guidelines of the institutional Ethics Committee and followed recommendations for the ethical care and use of laboratory animals

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Pharmacological inhibition of TrkB by subchronic intrastriatal administration of k252a rescued behavioral alterations in Bsn mutant mice and prevented the occurrence of pathological form of plasticity in fast-spiking interneurons

They mimic the action of endogenous GLP-1, a hormone naturally released by cells in the small intestine in response to food intake and exert effects 16 (Figure 1) in a dose-dependent manner 17

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