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Nos estudos animais, as doses eficazes situam-se entre 10 g/kg e 10 ng/kg (via oral ou subcutnea)

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The study, Efficacy and Safety of Ultrahigh-Dose Methylcobalamin in Early-Stage Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial, was published in the journal JAMA Neurology